Psychological and physiological factors can contribute to premature ejaculation.

Psychological causes include:

• Predisposition.
• Reactive Depression.
• Stress.
• Relationship problems.
• Sexual performance anxiety (especially at the start of a new relationship or if there have been problems with performance in the past).
• History of sexual abuse.

Physiological causes include:

• Using recreational drugs.
• Hypersensitivity.
• Obesity.
• Thyroid problems.
• Low testosterone.
• Prostate or urethral problems.
• Nervous system problems e.g. multiple sclerosis or peripheral neuropathy.

This service is suitable for you if you are:

• 18-65 years of age.

• Male.

• Having symptoms of premature ejaculation. 

This service is not suitable for you if you:

• Are less than 18 years of age or more than 65 years of age.

• Are female.

• Or have significant kidney or liver disease. 

Also treatment options may be limited if 

• If you are taking certain types of antidepressant medication (SSRI, SNRI).

• Have a history of:

  • Bi-polar, mania or significant depression.

  • Heart problems such as heart failure, heart attack/ angina, arrhythmias or valve abnormalities.

  • Epilepsy.

  • Syncope/ fainting due to low blood pressure.

  • Glaucoma (raised eye pressure).

• Are using recreational drugs (there are potentially very serious interactions).

Webdoctor.ie provides prescriptions for Priligy (dapoxetine) tablets and EMLA cream, subject to clinical suitability. To make sure these treatments are medically safe and suitable for you, it is essential that you answer the medical assessment questionnaire honestly and accurately.

Priligy is an on-demand tablet treatment for premature ejaculation. It is taken 1-3 hours before sexual activity and should be effective for 2-4 hours.

You should not take Priligy more than once in 24 hours. It may be necessary to try this medication on 4-6 occasions before the full effects are evident. If it is not working after this trial, please speak with one of our doctors.

Priligy is a selective serotonin reuptake inhibitor (SSRI) and the active ingredient is dapoxetine. It works by increasing serotonin levels, causing a delayed reaction in the part of the brain that controls ejaculation. Priligy increases the time it takes to ejaculate and can improve control over the time of ejaculation for the majority (usually over 80%) of men.

SSRI/ SNRI medications can be used to treat depression/ anxiety symptoms. Priligy should not be taken if you are currently using these medications as this can result in potentially serious interactions. You should avoid taking anti-inflammatory medications when you are using Priligy.

If you are using medications to thin your blood (anticoagulation medications) you should really speak with your doctor before deciding to use this medication as it may increase your bleeding risk.

Priligy can lower your blood pressure and make you feel dizzy or faint. You should not drive or operate machinery if you feel dizzy or you have fainted.

Other common side effects may include headaches, nausea, diarrhoea or constipation.

Priligy can enhance the effects of alcohol and so, these should not be taken together.

If Priligy does not agree with you or you would prefer to not take tablets, EMLA might be an option.

EMLA is an anaesthetic cream. This is applied to the glands (or head) of the penis and causes the nerve fibres in the head to be numbed over the course of a few minutes. It should be applied about 20 minutes before sex, and the remaining cream washed off just before sex.

Common side effects include irritation, itch and numbness of genital skin for both you and your partner.

Please be aware that EMLA cream damages latex condoms.

This use of EMLA cream is referred to as an ‘off licence’ use. Nevertheless, it is a popular treatment for PE.

Every medicine must have a licence for its specified use, issued by the Irish Health Products Regulatory Authority. However, some medications have additional therapeutic uses outside of their intended use. EMLA is licensed to numb the skin for minor surgical procedures or needle insertion, but it is also used to numb the skin of the penis to help manage premature ejaculation.

If you are unsure which medication to try, our Clinical Director recommends you try Priligy first. Priligy has a high success rate, and many people find it more convenient to use than EMLA.

EMLA is an anaesthetic cream that needs to be washed off after application and before sexual activity. However, we are happy to provide a prescription for EMLA if Priligy does not provide satisfactory results.

When completing the questionnaire, please ensure you let us know exactly what medications you are taking (prescribed and over-the-counter) as Priligy has significant interactions with some drugs. This will enable us to advise you on appropriate treatments and prescribe them safely. 

You should not take more than one Priligy tablet in 24 hours. Avoid alcohol or recreational drugs with this medication due to potentially serious drug interactions. 

For full details on the potential side effects of your medication, please ensure that you read the patient information leaflet that comes with your medication before you start to use it for full details on potential side effects. 

If you are concerned that you are developing side effects, we advise that you stop your medication and seek medical advice

For further information on premature ejaculation and treatment options, visit  Ejaculation Problems – Sexual Advice Association