GLP-1 medications such as semaglutide and liraglutide are becoming increasingly popular in Ireland for managing type 2 diabetes and supporting weight loss. While they can be effective, it’s important to understand how they work, their side effects, and how to protect your health while taking them.
Here are five key facts you should know before starting GLP-1 treatment.
1. They Can Lead to Muscle Loss as Well as Fat Loss
GLP-1 medications work by helping you eat less and lose weight — but some of that weight can be muscle mass. Losing muscle can affect your strength, metabolism, and long-term health.
What to do:
- Include resistance exercise in your weekly routine
- Eat enough high-quality protein throughout the day
- Work with a dietitian to support muscle preservation during weight loss
2. Appetite Suppression Can Lead to Nutrient Gaps
GLP-1 medications reduce appetite, meaning you may eat smaller portions or fewer meals. This can make it harder to meet your nutritional needs.
What to do:
- Focus on balanced, nutrient-dense meals
- Prioritise protein, vegetables, and healthy fats in each serving
- Plan ahead to make every bite count
- Nausea and Diarrhoea Are Common Side Effects
Over 1 in 10 people experience nausea or diarrhoea while taking GLP-1 medications. This can affect your appetite and food choices, and may worsen muscle loss if eating becomes difficult.
What to do:
- Eat small, frequent meals instead of large portions
- Choose bland, easy-to-digest foods when feeling unwell
- Seek advice from your GP or dietitian if symptoms persist
4. Dehydration Is a Real Risk
Reduced appetite and digestive side effects can lead to dehydration, which can cause fatigue, headaches, and other complications.
What to do:
- Drink at least 1.5 to 2 litres of water daily, unless otherwise advised by your doctor
- Spread fluid intake throughout the day
- Include hydrating foods like soups and fresh fruit
5. You Need Ongoing Medical and Dietary Support
GLP-1 medications are not for self-prescription. Ongoing follow-up with your GP is essential to monitor your health, adjust your dose, and manage side effects.
What to do:
- Schedule regular GP check-ins or speak with one at Webdoctor
- Work with a registered dietitian to tailor your nutrition plan
- Avoid relying solely on medication — combine with healthy eating and physical activity for best results
Final Word and How Webdoctor.ie Can Help
GLP-1 medications can be a helpful tool for weight management and diabetes care, but they work best when combined with the right diet, hydration, and physical activity. Always use them under the supervision of a healthcare professional.
If you need weight management support, Webdoctor offers an online prescription service for GLP-1 medications, with safe, regulated prescribing from our Irish GPs. You can also talk with a specialised weight management GP, book your consultation.
You can also speak directly to one of our registered dietitians — no referral needed, and no waiting list — to get personalised nutrition guidance for your journey.
Start your personalised plan today: